Extracts from British Medical Formulary
Local anaesthetic drugs act by causing a reversible block to conduction along nerve fibres. The smaller the nerve fibre, the more sensitive it is, so that a differential block may occur where smaller fibres carrying pain sensation and autonomic impulses are blocked. The drugs used vary widely in potency, duration of action, stability, solubility in water and ability to penetrate the mucous membranes. These variations determine the suitability for use by various routes for example topical infiltration or plexus or spinal block.
Toxic effects associated with a local anaesthetic are usually a result of excessively high plasma concentration. The main effects are excitation of the Central Nervous System. [nervousness, nausea and convulsions] followed by depression. Less commonly the cardio vascular system is depressed. A hyper sensitivity reaction occurs mainly with the Ester type local anaesthetic such as Amethocaine, Benzocaine, cocaine and procaine: reactions are less frequent with the amide types such as lignocaine, bupivocaine and Prilocaine.
Toxicity may occur with repeated dosage due to accumulation of the drug, and reduced doses should therefore be given. Toxic effects may also occur if the injection is too rapid. Local anaesthetic should not be injected into inflamed or infected tissue nor should they be applied to the traumatised urethra. Under these conditions the drug may be so rapidly absorbed that a systemic rather than a local reaction is produced.
Most local anaesthetics, with the exception of cocaine cause dilation of the blood vessels. The addition of vasoconstrictors such as adrenalin diminishes local blood flow, slows the rate of absorption of the local anaesthetic and prolongs its local effect. Care is necessary when using adrenalin for this purpose because in excess it may produce ischaemic necrosis.
Cautions: Epilepsy, hepatic
impairment, impaired cardiac conduction, bradycardia.
Side effects: Hypotension,
bradycardio. Cardiac arrest. CNS effects include agitation, euphoria,
respiratory depression convulsions.
Bupivocaine Hydrochloride [Epidural]
Cautions and side effects
See under Lignocaine and
general notes.
Myocardial depression may be
more severe and more resistant to treatment
Prilocaine Hydrochloride
Dental use
Citanest
Cautions and side effects
See under Lignocaine and
general notes.
Pethedine Hydrochoride.
Most commonly used during
childbirth and for pain relief.
Cautions:
Chronic respiratory disease,
myasthenia gravis.
Side effects:
Respiratory depression
transient hypotension, Bradycardia, nausea vomiting
Tricyclic antidepressants
Amytriptiline Hydrochloride
Caution: Diabetes cardiac
disease, epilepsy,pregnancy and breast feeding, hepatic impairment, thyroid
disease, psychosis, glaucoma, urinary retention.
Contra indications: recent
myocardial infarction, heart block, mania, porphyria.
Side effects: Dry Mouth,
sedation, blurred vision, constipation, nausea, difficulty with micturition,
cardiovascular arrythmias, postural hypotension, tachycardia, syncope,
particularly with higher dosage, sweating, tremor, rashes, behavioural
disturbances, hypomania, confusion, interference with sexual function, blood
sugar and weight changes.
Less common Black tongue,
parlytic ileus, convulsions, agranulocytosis, leucopenia, eosonophilia,
purpura, thrombocytopenia and jaundice.
Drugs in this category are
numerous. Some of the most commonly used are Amoxapine, Butriptyline,
Clomipramine, Anafranil, fluoxetine Hydrochloride, prozac and Seroxat, Eflexor
Symptoms: As above including
leucocyte disturbances.
Heart: Calcium-channel
blockers [BNF 2.6.2]
Heart and conduction system
Calcium Channel Blockers
interfere with the inward dispacementof calcium ions through the slow channels
of active cell membranes, they influence the myocardial cells, the cells within
the specialised conduction system of the heart and the cells of the vascular
smooth muscle.
Ditiazem Hydrochloride.
Caution: reduce dose in
hepatic and renal impairment.
Side effects: Bradycardia,
first degree heart block, hypotension, ankle oedema, headache, nausea, rashes.
[Toxic erythema reported]
Verapamil. Nifedipine Adalat.
Nicardipine-Cardine, Isradipione, Diltiazem.
Hay fever: Cyphroheptadine
Hydrochloride, Triprolidine Hydrochloride, Promethazane Hydrochloride,
Phenergen Diphenidramine Hydrochloride, Hystril, Lergoban
Side effects As above.
Antacids: Tagermat, Zantac
Actifed.
Side effects: as above.
Skin: Betnovate Hydrochlor
Side effects: dermal distress,
increased use may result in hormonal imbalance.
Cough Medicines: Benylate
Side effects: headache,
nausea.
Phytobiophysics research
Conducted by Prof Dame Diana Mossop through EAV analysis has shown conclusively that the above mentioned group of drugs known as Hydrochlorides have a disturbing long term effect on the body function causing numerous symptoms. The British National Formulary states that anaesthetic act by causing a reversal block to conduction along the fibres. EAV analysis has shown that whilst a reversal block may be created locally the anaesthetic rapidly becomes systematic causing a semi-permanent, and in some cases a permanent block to fibres in the autonomic and central nervous system with resultant related symptomology.
The presence of the anaesthetic in the nervous system interferes with plexus function causing numerous symptoms depending on the variation of the anaesthetic administered, the area of administration and other factors dependant on the health of the patient and the accumulation of other Hydrochloride drugs.
All Hydrochloride drugs have an accumulative effect with the symptoms becoming more severe with increased prescription. It has also been shown conclusively that drugs administered to the mother during childbirth such as Epidural anaesthetic and Pethedine will have an effect on the baby Whilst the symptoms vary accordingly the most common appears to be respiratory distress which leads to Asthma, Eczema and an increased level of vulnerability which in turns leads to an inability to respond favourably to the first of the childhood vaccines BCG, often administered in UK within the first few days of life.
It is somewhat worrying that with the increased popularity of these childbirth drugs, the statistical reports with regard to children with asthma and eczema show a very rapid increase in the numbers of children diagnosed with these symptoms, and worse such as blood platelet disorders which has led to a new follow up procedure referred to as Vit K. This procedure is recommended after birth by Epidural but has now become the norm regardless of whether the mother has had intervention or not.
Symptoms which have been linked to Hydrochloride administration by Phytobiophysics research.
The majority of symptoms are mentioned as side effects by the British National Formulary, which also states that accumulation of the drug may occur with repeated dosage and reduced dosages should therefore be given. However what is not mentioned is the danger of the accumulative effects of all the Hydrochloride drugs.
The list of Hydrochloride drugs is extensive and ranges from anaesthesia, dental injections to children’s sedative drugs such as calpol, topical drugs for eczema and cough medicines etc. In consequence assessing the accumulation of the drug is virtually impossible because hydrochloride drugs are so widely used by doctors dentists and during hospitalisation, not to mention the prescription drugs such Beta blockers and antidepressants and many non prescription drugs bought over the counter.
Unless by EAV, it is virtually impossible to assess this accumulative factor.
Symptoms assessed by EAV.
Central Nervous system Excitation.
Epilepsy, headache, migraine, eyestrain, dystonia.
Structural disorders, TMJ misalignment, cranio-sacral misalignment.
Autonomic Nervous System: Sedation, depression, hypo function and emotional trauma. Increased likelihood of Meningitis and nervous system disorders.
Lungs: Emphysemia, asthma and respiratory distress
Circulatory disorders: Anuerysm, polyarteritis, embolism, cardiac failure, congestive heart failure, angina, fibrillation, myocardial infarct, cardiac arythmia, thrombosis and blood coagulation defects such as varicosity.
Liver disorders ranging from hepatoxicity, hepatic encephalopathy, portal hypo tension, oedema and kidney failure.
Kidneys: Nephritis and inflammation, kidney failure.
Digestive disorders including pancreatitis, hypoglycaemia and weight gain.
Bone disorders: Osteomalacia and rheumatic arthritis.
Colonic: Constipation, malabsorption, Colitis, Irritable Bowel Syndrome leading to chronicity and diarrhoea.
Skin and connective tissue: ulcers,, cold sores and unexplained skin disorders such as dermatitis, eczema, hives and rashes.
Reproductive organs: Impotence and lack of sexual enjoyment. Hydrochloride causes a spasm in Cervical 2/3 which results in a corresponding spasm between lumbar 4/5, This plexus inter relates with the function of the trigonal sphincter which controls erection [penis] orgasm and the muscles of the nervous system of the vagina. This condition is particularly severe after Epidural which is administered into the Epidural space between lumbar 4/5.
Hormonal imbalance:
Pineal control of the parathyroid production of the hormone Calcitonin.
Endocrine: production of the thyroid hormone Thyro-calcitonin.
Spleen function: RES haemolysis action of breakdown of haemoglobin.
Blood: disorders of the blood platelets. Bruising varicosity haemorrhoids, blood clotting factor disorders.
RNA damage to the bone marrow and production of Basophil Stem Cells leading to severe breakdown of the immune system and the production of Thymopoetin T8 Suppressor cells. Basophils are the prophylactic blood cells. They prevent disease by triggering immune system production of thymus hormones when the body encounters invasive bacteria, antigens and pathogens. Hence Basophils play an important role in ensuring a healthy immune system.
Basophils produce Histamine response. Basophil reduction causing serious allergy response and anaphylactic shock [such as the severe reaction to bee and wasp stings and injections, increased likelihood of nut allergy.] Anaphylactic shock increases with each subsequent contact with the allergen or procedure
Anaemia: Hypochromic, megaloblastic and aplastic anaemia.
Prostaglandins: Prostoic acid leading to deficiency of Immunoglobulin IG. M, Cortisol production and haemoglobin.
PF3a related to Immunoglobulin [IG] A :ANS function
Arachidonic Acid related to Immunoglobulin IG. G: lung function
Digestive Enzyme Disturbance: HCL leading to acidosis and heart disorders, ulcers and decreased production of other stomach enzymes:
Motilin causing liver disorders and fails to trigger production of pancreatic Nuclease and small intestine Nucleatidase.
SI Nucleatidase metabolises amino acids:
l-Threonine supports liver function, nervous system and glucose tolerance factor
l-Ornithine assists Vit A absorption for healthy mucous membranes, bones, eyes and skin. Kidney function
l-Glycine healthy heart valve function lung function , absorption of B1 Thiamine and ANS.
Cranial Nerves affected:
CNV11 Right Facial particularly damaged by Dental Citanest
CNX Vagus Nerve particularly by Epidural and local anaesthetic.
Bupivacaine Hydrochloride
Specific Side effects linked to Epidural administration include all the symptoms of Hydrochloride administration and increase with each administration.
In some cases the Epidural is not effective and the dosage is increased during the procedure. This practise is very worrying as the symptoms become more complex and since the Bupivocaine is known to cross the placental barrier Epidural administered during child birth has many severe repercussions in the long term health of the child. Current research has shown that babies born with medical intervention have a far greater likelihood of suffering with a wide range of childhood disorders including lowered immunity and a pre disposition to Autism.
Specific symptoms of Epidural.
Increased likelihood of Cervical cancer;
Statistical evidence shows that one in five young women who have had Epidural administered during childbirth is now suffering with CIN ranging from CIN 1 to 3. As a result of these statistics young mothers are automatically screened for Cervical cancer post childbirth. [Despite this statistical evidence patients are not advised of the possible side effects and in many maternity hospitals Epidural is now offered as an automatic form of pain relief regardless of whether or not it is necessary.
Bones: Achondroplasia, osteomalacia, osteogenic imperfection, bone exotosis, bone tumour. Polyarthritis and bunions.
Liver: Toxic jaundice and Cholecystitis.
Reproductive organs: Impotence and lack of sexual enjoyment. Hydrochloride causes a spasm in Cervical 2/3 which results in a corresponding spasm between lumbar 4/5, This plexus inter relates with the function of the trigonal sphincter which controls erection [penis] orgasm and the muscles of the nervous system of the vagina. This condition is particularly severe after Epidural.The procedure takes it’s name from the epidural space surrounding the spinal cord and is administered into the Epidural space between lumbar 4/5.
Blood coagulation defects: Due to the increased level of blood platelet disorders particularly in the children born with Epidural the Vit K injection has now been introduced to counter this disorder.
The symptoms of platelet disorders range from spontaneous bruising, poor wound healing, epilepsy lack of sleep, and much more seriously bone marrow disorders such as leukaemia.
The Senior midwife of the Jersey General Hospital Maternity Ward [ Vicky Croxford] made several observations:
Babies born with medical intervention do not bond easily with their mothers, they cry a lot and appear unsettled with the result that many mothers give up breast feeding due to failure of milk.
Research has shown that this is due to an increased likelihood of Prolactinaemia. Not only does this interfere with breast-feeding but may in some cases cause infertility which would exclude the family from having more children.
Babies administered with Vit
K.
Due to the high levels of
platelet disorders in the babies born with these procedures it is now
recommended that babies born with Epidural are injected with Vit K or this is
administered via the mouth
Leading to serious breakdown in the brain hormone path and the Serotonin, Fibrinogin, Cholecystekinin path. Babies who are administered with this vaccine often react by screaming with a high pitched screech. This tone of cry is very disturbing to the mother who will react by becoming highly tense and this automatically stresses her. Because the cry is unnatural and the baby is often in pain they then fail to sleep and the mother not only ceases to be able to breast feed but often finds herself feeling extremely tired, highly strung, emotional and exhausted. Intensive research has shown that this causes a break down in the relationship between mother and child which frequently leads to serious emotional repercussions later in life.